Jimmy Garoppolo Throws For FOUR Touchdowns As San Franciscos’ Offense Has A Field Day Against Cards’


49ers 38-10 Cardinals: Jimmy Garoppolo throws for FOUR touchdowns as San Francisco’s offense has a picnic in Mexico City to pull off an impressive win


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Jimmy Garoppolo threw four touchdown passes, including two to Brandon Aiyuk and George Kittle, and the San Francisco 49ers won their third straight game by beating the Arizona Cardinals 38-10 on Monday night in Mexico City.

It was the fifth NFL regular season game played in Mexico City and the first since 2019. Technically a Cardinals home game, the announced raucous and festive crowd of 78,427 fans at Estadio Azteca heavily favored the 49ers, roaring particularly loud when Kittle and Deebo Samuel each scored on 39-yard touchdowns.

San Francisco (6-4) has won five of its last seven and is tied with the Seahawks for the top spot in the NFC West. Garoppolo turned in another efficient performance, completing 20 of 29 passes for 228 yards.

Deebo Samuel carries the ball against the Arizona Cardinals during the third quarter

Jimmy Garoppolo throws a pass during the first half of an NFL football game against the Arizona Cardinals

Jimmy Garoppolo throws a pass during the first half of an NFL football game against the Arizona Cardinals

It was a close game for much of the first half, but the 49ers pulled away in the second half, jumping out 24-10 early in the third quarter on a clever final play. Samuel took the throw and ran for 39 yards, blasting through the Cardinals’ defense on his way to the end zone.

It capped a powerful eight-play San Francisco drive that included seven runs. Aiyuk’s second touchdown catch of the night, this one from 14 yards, put the 49ers up 31-10 later in the third.

Brandon Aiyuk and his teammates celebrate his touchdown reception against the Arizona Cardinals

Brandon Aiyuk and his teammates celebrate his touchdown reception against the Arizona Cardinals

The Cardinals (4-7) played their second straight game without Pro Bowl quarterback Kyler Murray, who has been battling hamstring pain. Backup Colt McCoy had a 3-1 record in spot starts over the past two seasons, including a win over the Rams last week, but he couldn’t recreate the same magic in Mexico.

McCoy finished 24 of 34 passing for 218 yards and one interception. The 49ers hit him hard several times, connecting for three sacks.

The 49ers took a 17-10 lead at the halftime break after Robbie Gould hit a 39-yard field goal with 43 seconds remaining in the second quarter. It capped off a back-and-forth first half in which the teams gained nearly identical amounts of yardage: the 49ers led 186-185.

Colt McCoy is sacked by San Francisco 49ers defensive tackle Kevin Givens during the second half

Colt McCoy is sacked by San Francisco 49ers defensive tackle Kevin Givens during the second half

The Cardinals advanced 3-0 midway through the first quarter on Matt Prater’s 40-yard field goal as both teams dealt with a steady rain that started around kickoff and continued for much of the first half.

The 49ers responded early in the second when Garoppolo hit Aiyuk up the middle for a 7-yard touchdown run, capping a nine-play, 82-yard drive. San Francisco intercepted McCoy on the ensuing drive after a pass ricocheted off James Conner’s hand and was caught by Jimmie Ward in the air.

San Francisco capitalized three plays later when Garoppolo evaded the pressure and threw a pass to Kittle, who hit two Arizona defenders and then drove into the end zone for a 39-yard touchdown run and a 14-3 lead.

Home to two of Mexico’s best soccer teams, the cavernous Estadio Azteca sits at an altitude of approximately 7,200 feet, which is much higher than San Francisco and Phoenix. The 49ers opted to train at altitude this week in Colorado, while the Cardinals decided to stay at their home practice facility in Tempe, Arizona.

Arizona’s defense seemed gassed in the second half, missing several tackles as the game got out of hand.

George Kittle (85) celebrates his touchdown reception against the Arizona Cardinals during the fourth quarter

George Kittle (85) celebrates his touchdown reception against the Arizona Cardinals during the fourth quarter

Christian McCaffrey (23) drives the ball past Arizona Cardinals linebacker Tanner Vallejo (51)

Christian McCaffrey (23) drives the ball past Arizona Cardinals linebacker Tanner Vallejo (51)

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